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Альтернативный метод контрастирования в оптической когерентной томографии: оценка синхронности мигания спеклов

Альтернативный метод контрастирования в оптической когерентной томографии: оценка синхронности мигания спеклов

Demidov V., Demidova O., Shabunin A., Vitkin I.A.
Ключевые слова: медицинская визуализация; оптическая когерентная томография; спекл-синхронизация; контрастирование изображений; обработка изображений; характеристика тканей; временная декорреляция.
2018, том 10, номер 1, стр. 39.

Полный текст статьи

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В данной работе предлагается к рассмотрению альтернативный метод контрастирования в оптической когерентной томографии (ОКТ), основанный на оценке синхронности мигания спеклов структурных ОКТ B-сканов. Показано, что изменения в степени синхронизации мигания спеклов во времени могут быть использованы для выделения различных типов тканей, представляя таким образом новое эффективное контрастирование в ОКТ-визуализации.

Разработанная методика проверена на рассеивающих потоковых фантомах и in vivo на раковой опухоли шейки матки, выращенной в смоделированном отверстии дорсальной поверхности кожи мыши. Проведено показательное сравнение полученных значений степени синхронизации спеклов с результатами анализа автокорреляционной функции для демонстрации ее отличий. Фантомные и доклинические результаты in vivo показывают, что предлагаемый синхронизационный подход чувствителен к типу ткани/патологии и позволяет осуществлять количественную оценку опухоли и ее выделение на фоне окружающих здоровых тканей.

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Demidov V., Demidova O., Shabunin A., Vitkin I.A. Alternative Contrast Mechanism in Optical Coherence Tomography: Temporal Speckle Synchronization Effects. Sovremennye tehnologii v medicine 2018; 10(1): 39, https://doi.org/10.17691/stm2018.10.1.05


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