Today: Apr 2, 2023
Last update: Feb 28, 2023
Inflammatory Complications of the Abdominal Wall Prosthetic Repair: Diagnostics, Treatment, and Prevention (Review)

Inflammatory Complications of the Abdominal Wall Prosthetic Repair: Diagnostics, Treatment, and Prevention (Review)

Parshikov V.V.
Key words: hernia; prosthetic repair; mesh; abdominal wall reconstruction; endoprosthesis; complications of prosthetic repair; paraprosthetic infection; NPWT.
2019, volume 11, issue 3, page 158.

Full text

html pdf

A number of issues in diagnosis, treatment, and prevention of purulent and septic complications in implantation of mesh are currently very far from being resolved. Patients with acute or chronic inflammatory processes associated with a mesh are of special concern, as this situation can completely discredit the possibilities of the abdominal wall reconstruction and the use of synthetic materials for this purpose, casting doubt on the accumulated knowledge, experience of the clinic and the surgeons’ qualification.

Hereinafter the most up-to-date and clarified classifications of inflammatory complications are demonstrated. A systemic approach to the problem of clear stratification of patients depending on the risk of complication is provided. Differences and controversial opinions regarding terminology, latest concepts and definitions in the surgery of abdominal wall hernias are presented.

Possibilities of anticipating potential complications are specified. Identification of a special group of patients with large and complex, multiple defects of the abdominal wall is justified. The most effective methods of diagnosing the complications and the results of their application are assessed.

The definitions of an acute inflammatory process associated with endoprosthesis implantation and of a chronic paraprosthetic infection are given. The modern approaches to treatment including generally accepted methods and controversial opinions are described. Options of mesh excision, repeated prosthetic repair of the abdominal wall are presented; successes and failures depending on the chosen strategy are shown. The strategy of endoprosthesis saving is grounded; the underlying methods (NPWT — negative pressure wound therapy), their benefits and drawbacks are described. The most important areas of prevention of purulent and septic complications in herniology are specified.

Technical issues including the comparison of surgical methods, a certain range of techniques that can objectively eliminate the existing risks are provided. A specificity of endoprosthesis choice depending on the accumulated findings about mesh material, its manufacturing methods and properties is emphasized. The concept of implant prophylaxis is disclosed.

  1. Deerenberg E.B., Timmermans L., Hogerzeil D.P., Slieker J.C., Eilers P.H., Jeekel J., Lange J.F. A systematic review of the surgical treatment of large incisional hernia. Hernia 2015; 19(1): 89–101,
  2. Vorst A.L., Kaoutzanis C., Carbonell A.M., Franz M.G. Evolution and advances in laparoscopic ventral and incisional hernia repair. World J Gastrointest Surg 2015; 7(11): 293–305,
  3. Payne R., Aldwinckle J., Ward S. Meta-analysis of randomised trials comparing the use of prophylactic mesh to standard midline closure in the reduction of incisional herniae. Hernia 2017; 21(6): 843–853,
  4. Jensen K.K. Recovery after abdominal wall reconstruction. Dan Med J 2017; 64(3): B5349.
  5. Hodgkinson J.D., Maeda Y., Leo C.A., Warusavitarne J., Vaizey C.J. Complex abdominal wall reconstruction in the setting of active infection and contamination: a systematic review of hernia and fistula recurrence rates. Colorectal Dis 2017; 19(4): 319–330,
  6. Petukhova I.N., Sokolovskiy A.V., Grigor’evskaya Z.V., Bagirova N.S., Tereshchenko I.V., Varlan G.V., Aginova V.V., Dmitrieva N.V. Infections associated with placement of foreign materials (prostheses, meshes, implants). Zlokachestvennye opukholi 2017; 7(3–S1): 57–60.
  7. Birolini C., de Miranda J.S., Utiyama E.M., Rasslan S. A retrospective review and observations over a 16-year clinical experience on the surgical treatment of chronic mesh infection. What about replacing a synthetic mesh on the infected surgical field? Hernia 2015; 19(2): 239–246,
  8. Birolini C., de Miranda J.S., Utiyama E.M., Rasslan S., Birolini D. Active Staphylococcus aureus infection: Is it a contra-indication to the repair of complex hernias with synthetic mesh? A prospective observational study on the outcomes of synthetic mesh replacement, in patients with chronic mesh infection caused by Staphylococcus aureus. Int J Surg 2016; 28: 56–62,
  9. Hicks C.W., Blatnik J.A., Krpata D.M., Novitsky Y.W., Rosen M.J. History of methicillin-resistant Staphylococcus aureus (MRSA) surgical site infection may not be a contraindication to ventral hernia repair with synthetic mesh: a preliminary report. Hernia 2014; 18(1): 65–70,
  10. Meagher H., Clarke Moloney M., Grace P.A. Conservative management of mesh-site infection in hernia repair surgery: a case series. Hernia 2015; 19(2): 231–237,
  11. Narkhede R., Shah N.M., Dalal P.R., Mangukia C., Dholaria S. Postoperative mesh infection — still a concern in laparoscopic era. Indian J Surg 2015; 77(4): 322–326,
  12. Filippou D. Late Ps. aeruginosa inguinal mesh infection 12 years after the initial operation: report of the case and short review of the literature. Case Rep Surg 2017; 2017: 4385913,
  13. Chung L., Tse G.H., O’Dwyer P.J. Outcome of patients with chronic mesh infection following abdominal wall hernia repair. Hernia 2014; 18(5): 701–704,
  14. Luhmann A., Moses A. Successful conservative treatment of a candida albicans intraperitoneal mesh infection following laparoscopic ventral hernia repair. Hernia 2015; 19(5): 845–847,
  15. Zhukovskiy V.A. Polymer implants for reconstructive surgery. Innova 2016; 2(3): 51–59.
  16. Reśliński A., Dąbrowiecki S., Głowacka K. The impact of diclofenac and ibuprofen on biofilm formation on the surface of polypropylene mesh. Hernia 2015; 19(2): 179–185,
  17. Zakhidova S.Kh. Mistakes and complications associated with tension-free hernioplasty of strangulated postoperative ventral hernias. Tyumenskiy meditsinskiy zhurnal 2014; 4(16): 55–56.
  18. Tashtemirova O., Abitanova A., Zhakupova G. Analysis of surgical treatment of ventral hernia for patients with obesity. Nauka i zdravookhranenie 2013; 6: 61–64.
  19. Tubre D.J., Schroeder A.D., Estes J., Eisenga J., Fitzgibbons R.J. Jr. Surgical site infection: the “Achilles Heel” of all types of abdominal wall hernia reconstruction. Hernia 2018; 22(6): 1003–1013,
  20. Cherepanin A.I., Povetkin A.P., Lutsevich O.E. Atlas oslozhneniy khirurgii gryzh peredney bryushnoy stenki [Atlas of surgical complications of anterior abdominal wall hernias]. Moscow: GEOTAR-Media; 2017; 208 p.
  21. Köckerling F., Schug-Pass C., Scheuerlein H. What is the current knowledge about sublay/retro-rectus repair of incisional hernias? Front Surg 2018; 5: 47,
  22. Petro C.C., Novitsky Y.W. Classification of hernias. In: Hernia surgery. Springer International Publishing; 2016; p. 15–21,
  23. Köckerling F., Scheuerlein H., Schug-Pass C. Treatment of large incisional hernias in sandwich technique — a review of the literature. Front Surg 2018; 5: 37,
  24. Ozaki K., Tanimura K., Ebina Y., Kanemitsu K., Yamada H. A pregnant woman with a surgical site infection after mesh repair of an abdominal wall incisional hernia: a case report. J Med Case Rep 2017; 11(1): 66,
  25. Doran H., Costache A., Mustăţea P., Pătraşcu T. Enterocutaneous fistula occurring 15 years after the prosthetic mesh repair of a recurrent incisional hernia — a case report. Chirurgia (Bucur) 2015; 110(5): 478–481.
  26. Asano H., Yajima S., Hosoi Y., Takagi M., Fukano H., Ohara Y., Shinozuka N., Ichimura T. Mesh penetrating the cecum and bladder following inguinal hernia surgery: a case report. J Med Case Rep 2017; 11(1): 260,
  27. Degheili J.A., Hosn M.A., Lakis M.E., Hallal A.H. Sigmoid to scrotal fistula secondary to mesh erosion: a rare complication of inguinal hernia repair in a patient on anticoagulation. BMC Surg 2015; 15: 94,
  28. Liu S., Zhou X.-X., Li L., Yu M.-S., Zhang H., Zhong W.X., Ji F. Mesh migration into the sigmoid colon after inguinal hernia repair presenting as a colonic polyp: a case report and review of literature. World J Clin Cases 2018; 6(12): 564–569,
  29. Dubbeling R.M., Ramesh K. Infected inguinal hernia mesh presenting as pseudotumor of the bladder. Indian J Urol 2013; 29(4): 345–347,
  30. Ishikawa S., Kawano T., Karashima R., Arita T., Yagi Y., Hirota M. A case of mesh plug migration into the bladder 5 years after hernia repair. Surg Case Rep 2015; 1: 4,
  31. Bazaev A.V., Goshadze K.A., Malov A.A., Yanyshev A.A. Migration of polypropylene mesh into the abdominal cavity after hernia repair of recurrent postoperative ventral hernia (clinical case). Vestnik novyh medicinskih tehnologij 2016; 23(1): 59–61.
  32. Aggarwal S., Praneeth K., Rathore Y., Waran V., Singh P. Laparoscopic management of mesh erosion into small bowel and urinary bladder following total extra-peritoneal repair of inguinal hernia. J Minim Access Surg 2016; 12(1): 79–82,
  33. Koyama M., Miyagawa Y., Yamamoto Y., Kitazawa M., Suzuki A., Ishizone S., Miyagawa S. Surgery for chronic mesh infection occurred 10 years after sacrectomy — mesh resection and mesentric leaf repair: a case report. Int J Surg Case Rep 2017; 30: 215–217,
  34. Shrivastava A., Gupta A., Gupta A., Shrivastava J. Erosion of small intestine with necrotising fasciitis of over lying abdominal wall after expanded poly-tetrafluoroethylene mesh implantation: a rare complication after laparoscopic incisional hernia repair. J Minim Access Surg 2013; 9(3): 138–140,
  35. Dinc T., Kayilioglu S.I., Sozen I., Yildiz B.D., Coskun F. Fournier’s gangrene as a postoperative complication of inguinal hernia repair. Case Rep Surg 2014; 2014: 408217,
  36. Merali N., Almeida R.A., Hussain A. A case report on management of synergistic gangrene following an incisional abdominal hernia repair in an immunocompromised obese patient. Int J Surg Case Rep 2015; 15: 99–102,
  37. Eriksson A., Rosenberg J., Bisgaard T. Surgical treatment for giant incisional hernia: a qualitative systematic review. Hernia 2014; 18(1): 31–38,
  38. Babazhanov A.S., Akhmedov G.K., Obidov Sh.H. Means of optimization of operative therapy of postsurgical ventral hernia at patients with III–IV degree obesity. Nauka i mir 2015; 7(23): 137–139.
  39. Zykov D.V., Khalyastov I.N., Chegurov V.I., Ovcharov A.V., Karapetyan G.N. Large incisional hernia in a patient with diabetes mellitus and Crohn’s disease: a case report. Vestnik meditsinskogo instituta “REAVIZ”: reabilitatsiya, vrach i zdorov’e 2018; 1(31): 75–78.
  40. Kao A.M., Arnold M.R., Augenstein V.A., Heniford B.T. Prevention and treatment strategies for mesh infection in abdominal wall reconstruction. Plast Reconstr Surg 2018; 142(3 Suppl): 149S–155S,
  41. Arinchev R.S. Prognozirovanie i profilaktika oslozhneniy v otdalennom posleoperatsionnom periode u bol’nykh s priznakami displazii soedinitel’noy tkani. Dis. … kand. med. nauk [Prediction and prevention of complications in the remote postoperative period in patients with the signs of connective tissue dysplasia. PhD Dissertation]. Tver’; 2018.
  42. Degovtsov E.N., Kolyadko P.V. Seromas as a complication of surgical treatment of incisional hernias of anterior abdominal wall using mesh implants: current state of the problem. Novosti khirurgii 2018; 26(1): 96–102.
  43. Belokonev V.I., Ponomareva J.V., Pushkin S.Y., Melentieva O.N., Gulyaev M.G. Potential predictors and morphological aspects of seroma development after plastic surgery of the anterior abdominal wall hernia. Novosti khirurgii 2014; 22(6): 665–670.
  44. Salamone G., Licari L., Agrusa A., Romano G., Cocorullo G., Gulotta G. Deep seroma after incisional hernia repair. Case reports and review of the literature. Ann Ital Chir 2015; 86: S2239253X15022938.
  45. Morales-Conde S. A new classification for seroma after laparoscopic ventral hernia repair. Hernia 2012; 16(3): 261–267,
  46. Babaev A.P., Guliaev M.G. Prevention of wound complications in patients with the implementation of prosthetic hernioplasty in a combined way. Aspirantskiy vestnik Povolzh’ya 2014; 5–6: 85–87.
  47. Sonis A.G., Grachev B.D., Stolyarov E.A., Ishutov I.V. Prevention and treatment of infection wound complications at prosthetic hernia repair. Rany i ranevye infektsii 2014; 1(2): 16–23.
  48. Obolenskiy V.N., Kharitonov S.V., Enokhov V.Yu., Ermolov A.A. Negative pressure wound therapy in comprehensive treatment of infected wound complication after tension-free hernioplasty. Khirurg 2015; 8: 25–32.
  49. Obolenskiy V.N., Enokhov V.Yu., Kharitonov S.V. Clinical efficacy of local negative pressure method for treatment of infectious wound complications after non-stretching hernioplasty. Meditsinskiy alfavit 2018; 9(346): 45–49.
  50. Parent B., Horn D., Jacobson L., Petersen R.P., Hinojosa M., Yates R., Wright A.S., Louie O. Wound morbidity in minimally invasive anterior component separation compared to transversus abdominis release. Plast Reconstr Surg 2017; 139(2): 472–479,
  51. DeBordJ., Novitsky Y., Fitzgibbons R., Miserez M., Montgomery A. SSI, SSO, SSE, SSOPI: the elusive language of complications in hernia surgery. Hernia 2018; 22(5): 737–738,
  52. Sahoo S., Haskins I.N., Huang L.C., Krpata D.M., Derwin K.A., Poulose B.K., Rosen M.J. Early wound morbidity after open ventral hernia repair with biosynthetic or polypropylene mesh. J Am Coll Surg 2017; 225(4): 472–480.e1,
  53. Rhemtulla I.A., Fischer J.P. Retromuscular sublay technique for ventral hernia repair. Semin Plast Surg 2018; 32(3): 120–126,
  54. Poruk K.E., Farrow N., Azar F., Burce K.K., Hicks C.W., Azoury S.C., Cornell P., Cooney C.M., Eckhauser F.E. Effect of hernia size on operative repair and post-operative outcomes after open ventral hernia repair. Hernia 2016; 20(6): 805–810,
  55. Blatnik J.A., Krpata D.M., Novitsky Y.W., Rosen M.J. Does a history of wound infection predict postoperative surgical site infection after ventral hernia repair? Am J Surg 2012; 203(3): 370–374,
  56. Vlasov A.V. The prediction of the probability of seroma development in case of endoprosthesis replacement of ventral hernias. Sovremennye problemy nauki i obrazovaniya 2013; 2. URL:
  57. Golovin R.V., Nikitin N.A., Prokopev E.S. Prognosis of development of complications of injuries after com-bined allohernia plastic interventions for postoperative ventral hernias of median localization. Sovremennye problemy nauki i obrazovaniya 2014; 2. URL:
  58. Vnukov P.V., Sheptunov Yu.M. The comparative strain characteristics of the subcutaneous tissue longitudinal and transverse paraumbilical wounds (experimental research). Vestnik eksperimental’noy i klinicheskoy khirurgii 2016; 9(2): 165–168.
  59. Cherkasov M.F., Khindikaynen A.Yu., Pomazkov A.A. Methods of diagnosis, prevention and treatment of complications of hernia repair. Astrakhanskiy meditsinskiy zhurnal 2016; 11(4): 50–64.
  60. Aleksandrenkov N.V., Mykhin A.S., Rebcovsky V.A., Leontev А.Е. Wound closure method at subaponeurotic plasty with polypropylene mesh of large postoperative ventral hernia. Novosti khirurgii 2013; 21(1): 88–93.
  61. Alishev O.T., Shaimardanov R.S., Makhmutova Y.R. Prevention of large and giant postoperative ventral hernia prosthetic hernioplasty postoperative complications. Kazanskij medicinskij zurnal 2013; 94(3): 417–420.
  62. Narezkin D.V., Sergeev E.V. Preventive methods of pyo-inflammatory wound complications in herniotomy of strangulated postoperative ventral hernias. Novosti khirurgii 2014; 22(6): 743–749.
  63. Salamone G., Licari L., Augello G., Campanella S., Falco N., Tutino R., Cocorullo G., Gullo R., Raspanti C., De Marco P., Porrello C., Profita G., Gulotta G. Deep SSI after mesh-mediated groin hernia repair: management and outcome in an emergency surgery department. G Chir 2017; 38(1): 41–45,
  64. Abbaszade T.N., Anisimov A.Yu. Diagnosis and prevention of early postoperative wound complications in patients with large ventral hernias. Meditsinskiy vestnik Bashkortostana 2013; 8(3): 21–25.
  65. Anisimov A.Yu., Abbaszade T.N. The thermography facilities in the diagnosis of early postoperative vulnerary complications at large ventra hernia repair. Dnevnik kazanskoy meditsinskoy shkoly 2015; 4(10): 5–9.
  66. Pearce A., Thornton L., Sutton P.A., Walsh C.J. Post-operative C-reactive protein profile following abdominal wall reconstruction with transversus abdominis posterior components separation. Int J Surg Case Rep 2017; 40: 17–19,
  67. Zurnadzhjants V.A., Topchiev M.A., Bondarev V.A., Kchibekov E.A., Serdyukov M.A. Assessment of the course of wound process under the strangulated hernias of the abdominal wall. Kubanskiy nauchnyy meditsinskiy vestnik 2013; 7(142): 132–133.
  68. Magomedov M.M., Magomedbekov R.E., Ismailov G.M. Systemic inflammatory response in alloplastic treatment of the inguinal hernias. Vestnik novyh medicinskih tehnologij. Elektronnoe izdanie 2017; 2: 139–144.
  69. Smarzh T.M., Kuznetsov A.V., Ryzhikova S.L., Druzhinina Yu.G., Autenshlyus A.I. Dynamics of cytokines of blood serum and wound discharge in the process of postoperative wound healing depending on the adaptive capabilities of the body. Elektronnyy nauchnyy zhurnal 2016; 9(12): 60–70.
  70. Smarzh T.M., Kuznetsov A.V., Shestakov V.V., Fedin E.N. The character of early postoperative complications and cytokine dynamics depending on the adaptive capabilities of the body. Al’manakh mirovoy nauki 2017; 5(20): 25–33.
  71. Levy S., Moszkowicz D., Poghosyan T., Beauchet A., Chandeze M., Vychnevskaia K., Peschaud F., Bouillot J. Comparison of complete versus partial mesh removal for the treatment of chronic mesh infection after abdominal wall hernia repair. Hernia 2018; 22(5): 773–779,
  72. Antonyuk S.M., Achrameev V.B., Andrienko I.B., Lucenko Yu.G., Grintsov G.A. Peculiarities of prophylaxis of postoperative complications in the alloplasty of large and giant postoperative ventral hernias. Universitetskaya klinika 2016; 12(2): 23–26.
  73. Izmailov A.G., Dobrokvashin S.V., Volkov D.E., Lukoyanychev Е.Е., Pyrkov V.A., Zakirov R.F., Davlet-Kildeev Sh.A. Device for punctures of cavity structures in postoperative period in patients with ventral hernias. Prakticheskaya meditsina 2016; 5(97): 73–76.
  74. Izmailov A.G., Dobrokvashin S.V., Volkov D.E., Pyrkov V.A., Zakirov R.F., Davlet-Kildeev S.A., Akhmetzyanov R.F. Concept of prevention and treatment of postoperative wound complications in surgical patients. Prakticheskaya meditsina 2017; 6(107): 50–54.
  75. Shubinets V., Carney M.J., Colen D.L., Mirzabeigi M.N., Weissler J.M., Lanni M.A., Braslow B.M., Fischer J.P., Kovach S.J. Management of infected mesh after abdominal hernia repair: systematic review and single-institution experience. Ann Plast Surg 2018; 80(2): 145–153,
  76. Sharma R., Fadaee N., Zarrinkhoo E., Towfigh S. Why we remove mesh. Hernia 2018; 22(6): 953–959,
  77. Kalish Yu.I., Ametov L.Z., Shayusupov A.R., Yigitaliev S.Kh., Kabulov M.K. Chronic paraprosthesis infection after allohernioplasty. Medichnі perspektivi 2016; 21(4): 62–66.
  78. Chen T., Zhang Y.H., Wang H.L., Chen W., Wang J. Late-onset deep mesh infection: a study of eight cases detected from 2666 consecutive patients with abdominal wall hernia repairs. Chin Med J (Engl) 2016; 129(15): 1870–1872,
  79. Hanna M., Dissanaike S. Mesh ingrowth with concomitant bacterial infection resulting in inability to explant: a failure of mesh salvage. Hernia 2015; 19(2): 339–344,
  80. Panteleev V.S., Zavarukhin V.A., Pogorelova M.P. The use of ultrasound when removing infected mesh implants after hernioplasty. Meditsinskiy vestnik Bashkortostana 2018; 2(74): 24–28.
  81. Panteleev V.S., Zavarukhin V.A., Pogorelova M.P. Ultrasonic excision of infected mesh implants after hernioplasty. Vestnik eksperimental’noy i klinicheskoy khirurgii 2018; 11(2): 101–104.
  82. Panteleyev V.S., Zavarukhin V.A., Pogorelova M.P. Ultrasonic excision of infected mesh implants after hernioplasty (clinical case). Kreativnaya khirurgiya i onkologiya 2017; 7(4): 68–72,
  83. Kugler N.W., Bobbs M., Webb T., Carver T.W., Milia D., Paul J.S. A dual-stage approach to contaminated, high-risk ventral hernia repairs. J Surg Res 2016; 204(1): 200–204,
  84. Bueno-Lledó J., Torregrosa-Gallud A., Sala-Hernandez A., Carbonell-Tatay F., Pastor P.G., Diana S.B., Hernández J.I. Predictors of mesh infection and explantation after abdominal wall hernia repair. Am J Surg 2017; 213(1): 50–57,
  85. El-Gazzaz G.H., Farag S.H., El-Sayd M.A., Mohamed H.H. The use of synthetic mesh in patients undergoing ventral hernia repair during colorectal resection: risk of infection and recurrence. Asian J Surg 2012; 35(4): 149–153,
  86. McNichols C.H.L., Diaconu S., Liang Y., Ikheloa E., Kumar S., Kumar S., Nam A., Rasko Y. Outcomes of ventral hernia repair with concomitant panniculectomy. Ann Plast Surg 2018; 80(4): 391–394,
  87. Nobaek S., Rogmark P., Petersson U. Negative pressure wound therapy for treatment of mesh infection after abdominal surgery: long-term results and patient-reported outcome. Scand J Surg 2017; 106(4): 285–293,
  88. Berrevoet F., Vanlander A., Sainz-Barriga M., Rogiers X., Troisi R. Infected large pore meshes may be salvaged by topical negative pressure therapy. Hernia 2013; 17(1): 67–73,
  89. Jakob M.O., Schwarz C., Haltmeier, T., Zindel J., Pinworasarn T., Candinas D., Starlinger P., Beldi G. Mesh-augmented versus direct abdominal closure in patients undergoing open abdomen treatment. Hernia 2018; 22(5): 785–792,
  90. Chatzoulis G., Chatzoulis K., Spyridopoulos P., Pappas P., Ploumis A. Salvage of an infected titanium mesh in a large incisional ventral hernia using medicinal honey and vacuum-assisted closure: a case report and literature review. Hernia 2012; 16(4): 475–479,
  91. Bury K., Śmietański M., Justyna B., Gumiela P., Śmietańska A.I., Owczuk R., Naumiuk L., Samet A., Paradziej-Lukowicz J. Effects of macroporous monofilament mesh on infection in a contaminated field. Langenbecks Arch Surg 2014; 399(7): 873–877,
  92. Lysenko R.B. Prevention and treatment of wound complications at alloplasty of the complex abdominal wall defects. Zaporozhskij medicinskij zhurnal 2016; 3: 71–75,
  93. Al Daoud F., Thayer A., Sachwani Daswani G., Maraqa T., Perinjelil V., Mercer L. Jr. Management of chronic abdominal wall seroma with Doxycycline sclerotherapy using a Negative Pressure Wound Therapy System KCI-V.A.C.Ulta™ — a case report. Int J Surg Case Rep 2018; 51: 25–28,
  94. Khan S.I., Blumrosen G., Vecchio D., Golberg A., McCormack M.C., Yarmush M.L., Hamblin M.R., Austen W.G. Eradication of multidrug-resistant pseudomonas biofilm with pulsed electric fields. Biotechnol Bioeng 2016; 113(3): 643–650,
  95. Musaev A.I., Isaev E.B., Maksut u. E., Aliev M.J. Infection control in high risk departments. The economic significance of surgical site infection (literature review). Vestnik KGMA imeni I.K. Ahunbaeva 2018; 2: 58–63.
  96. Natsional’nye klinicheskie rekomendatsii po gerniologii “Pakhovye i posleoperatsionnye gryzhi” [National clinical guidelines on herniology “Inguinal and postoperative hernias”]. Pod red. Ettingera A.P., Shestakova A.L., Gogiya B.Sh. [Ettinger A.P., Shestakov A.L., Gogiya B.Sh. (editors)]. Moscow; 2018.
  97. Yakovlev S.V., Zhuravleva M.V., Protsenko D.N., Beloborodov V.B., Briko N.I., Brusina E.B., Gusarov V.G., Eliseeva E.V., Zamyatin M.N., Zyryanov S.K., Kukes V.G., Popov D.A., Sidorenko S.V., Suvorova M.P. Antibiotic stewardship program for inpatient care. Clinical guidelines for Moscow hospitals. Consilium Medicum 2017; 19 (7.1. Surgery): 15–51.
  98. Chattha A., Muste J., Patel A. The impact of hospital volume on clinical and economic outcomes in ventral hernia repair: an analysis with national policy implications. Hernia 2018; 22(5): 793–799,
  99. Cherla D.V., Holihan J.L., Flores-Gonzalez J.R., Lew D.F., Escamilla R.J., Ko T.C., Kao L.S., Liang M.K. Decreasing surgical site infections after ventral hernia repair: a quality-improvement initiative. Surg Infect (Larchmt) 2017; 18(7): 780–786,
  100. Heniford B.T., Ross S.W., Wormer B.A., Walters A.L., Lincourt A.E., Colavita P.D., Kercher K.W., Augenstein V.A. Preperitoneal ventral hernia repair: a decade long prospective observational study with analysis of 1023 patient outcomes. Ann Surg 2018,
  101. Saleh S., Plymale M.A., Davenport D.L., Roth J.S. Risk-assessment score and patient optimization as cost predictors for ventral hernia repair. J Am Coll Surg 2018; 226(4): 540-546,
  102. Gaedcke J., Schüler P., Brinker J., Quintel M., Ghadimi M. Emergency repair of giant inguinoscrotal hernia in a septic patient. J Gastrointest Surg 2013; 17(4): 837–839,
  103. Ponomareva Y.V., Volova L.T., Belokonev V.I. The role of tension factor inprosthetic materials biocompatiblity for hernioplasty. Vestnik meditsinskogo instituta “REAVIZ”: reabilitatsiya, vrach i zdorov’e 2016; 4(24): 66–72.
  104. Pushkin S.Yu., Belokonev V.I., Kovaleva Z.V., Grachev D.B., Gubskiy V.M. The relation between the complication after operations at patients with hernias and ways of hernioplasty and also follow-up diseases. Tol’yattinskiy meditsinskiy konsilium 2016; 3–4: 19–24.
  105. Belokonev V.I., Vavilov A.V., Guliaev M.G., Grachev D.B. Tactics of treatment of patients with recurrent postoperative incisional hernias. Tavricheskiy mediko-biologicheskiy vestnik 2018; 21(2): 17–23.
  106. Bratzler D.W., Dellinger E.P., Olsen K.M., Perl T.M., Auwaerter P.G., Bolon M.K., Fish D.N., Napolitano L.M., Sawyer R.G., Slain D., Steinberg J.P., Weinstein R.A. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Health Syst Pharm 2013; 70(3): 195–283,
  107. Poborsky A.N., Drozhzhin E.V., Ponamaryov N.I., Asutayev Sh.J. Pharmacological and economic feasibility of antibiotic therapy for herniatomy complications. Vestnik SurGU. Meditsina 2017; 1(31): 59–61.
  108. Korableva A.A., Ziganshina L.E. Basic principles of antibacterial prophylaxis in surgery: Cochrane evidence. The Journal of scientific articles “Health and Education Millennium” 2017; 19(7): 138–141,
  109. Ioannidis O., Paraskevas G., Varnalidis I., Ntoumpara M., Tsigkriki L., Gatzos S., Malakozis S., Papapostolou D., Papadopoulou A., Makrantonakis A., Makrantonakis N. Hernia mesh repair of the anterior abdominal wall and antibiotic chemoprophylaxis: multiple doses of antibiotics failed to prevent or reduce wound infection. Chirurgia (Bucur) 2013; 108(6): 835–839.
  110. Kokotovic D., Bisgaard T., Helgstrand F. Long-term recurrence and complications associated with elective incisional hernia repair. JAMA 2016; 316(15): 1575–1582,
  111. Belyansky I., Daes J., Radu V.G., Balasubramanian R., Reza Zahiri H., Weltz A.S., Sibia U.S., Park A., Novitsky Y. A novel approach using the enhanced-view totally extraperitoneal (eTEP) technique for laparoscopic retromuscular hernia repair. Surg Endosc 2018; 32(3): 1525–1532,
  112. Belyansky I., Reza Zahiri H., Sanford Z., Weltz A.S., Park A. Early operative outcomes of endoscopic (eTEP access) robotic-assisted retromuscular abdominal wall hernia repair. Hernia 2018; 22(5): 837–847,
  113. Albino F.P., Patel K.M., Nahabedian M.Y., Sosin M., Attinger C.E., Bhanot P. Does mesh location matter in abdominal wall reconstruction? A systematic review of the literature and a summary of recommendations. Plast Reconstr Surg 2013; 132(5): 1295–1304,
  114. Dietz U.A., Menzel S., Lock J., Wiegering A. The treatment of incisional hernia. Dtsch Arztebl Int 2018; 115(3): 31–37,
  115. Kukosh M.V., Vlasov A.V., Gomozov G.I. Prevention of early incisional complications in ventral hernia prosthetic repair. Novosti khirurgii 2012; 5: 32–37.
  116. Lembas A.N., Tampey I.I., Kuchinskiy M.V., Baulin A.V., Baulin V.A., Ivanchenko V.V., Velishko L.N., Velishko S.I., Pigovich I.B. Surgical treatment of recurrent incisional ventral hernias. Ukrainskiy zhurnal khirurgii 2013; 4(23): 59–63.
  117. Krivoschekov E.P., Molchanov M.A., Grigoryev S.G., Romanov V.E., Grigoryeva T.S. Intraoperative prophylactics of sustaining postoperative complications in IPOM-techniques in ventral and umbilical hernias. Aspirantskiy vestnik Povolzh’ya 2017; 1–2: 103–107.
  118. Naran S., Shakir S., Shestak K.C., Russavage J.M., Nguyen V.T. Components separation for abdominal wall reconstruction in the recalcitrant, high-comorbidity patient: a review of 311 single-surgeon cases. Ann Plast Surg 2018; 80(3): 262–267,
  119. Novitsky Y.W., Fayezizadeh M., Majumder A., Neupane R., Elliott H.L., Orenstein S.B. Outcomes of posterior component separation with transversus abdominis muscle release and synthetic mesh sublay reinforcement. Ann Surg 2016; 264(2): 226–232,
  120. Mommers E.H., Wegdam J.A., Nienhuijs S.W., de Vries Reilingh T.S. How to perform the endoscopically assisted components separation technique (ECST) for large ventral hernia repair. Hernia 2016; 20(3): 441–447,
  121. Muse T.O., Zwischenberger B.A., Miller M.T., Borman D.A., Davenport D.L., Roth J.S. Outcomes after ventral hernia repair using the rives-stoppa, endoscopic, and open component separation techniques. Am Surg 2018; 84(3): 433–437.
  122. Switzer N.J., Dykstra M.A., Gill R.S., Lim S., Lester E., de Gara C., Shi X., Birch D.W., Karmali S. Endoscopic versus open component separation: systematic review and meta-analysis. Surg Endosc 2015; 29(4): 787–795,
  123. Cornette B., De Bacquer D., Berrevoet F. Component separation technique for giant incisional hernia: a systematic review. Am J Surg 2018; 215(4): 719–726,
  124. Scheuerlein H., Thiessen A., Schug-Pass C., Köckerling F. What do we know about component separation techniques for abdominal wall hernia repair? Front Surg 2018; 5: 24,
  125. Malkov I.S., Mukhtarov Z.M., Malkova M.I. Methods of improving treatment results for patients with postoperative ventral hernia. Kazanskij medicinskij zurnal 2014; 95(4): 543–548.
  126. Mukhtarov Z.M., Malkov I.S., Alishev O.T. Prevention of wound postoperative complications in patients with postoperative ventral hernia. Prakticheskaya meditsina 2014; 5(81): 106–109.
  127. de Vries F.E.E., Atema J.J., Lapid O., Obdeijn M.C., Boermeester M.A. Closed incision prophylactic negative pressure wound therapy in patients undergoing major complex abdominal wall repair. Hernia 2017; 21(4): 583–589,
  128. Massey L.H., Pathak S., Bhargava A., Smart N.J., Daniels I.R. The use of adjuncts to reduce seroma in open incisional hernia repair: a systematic review. Hernia 2018; 22(2): 273–283,
  129. Gurusamy K.S., Allen V.B. Wound drains after incisional hernia repair. Cochrane Database Syst Rev 2013; 12: CD005570,
  130. Krpata D.M., Prabhu A.S., Carbonell A.M., Haskins I.N., Phillips S., Poulose B.K., Rosen M.J. Drain placement does not increase infectious complications after retromuscular ventral hernia repair with synthetic mesh: an AHSQC analysis. J Gastrointest Surg 2017; 21(12): 2083–2089,
  131. Anurov M.V., Titkova S.M., Oettinger A.P. Classification of prostheses for abdominal hernia repair: analytical literature review. Vestnik Rossiyskogo gosudarstvennogo meditsinskogo universiteta 2015; 1: 5–10.
  132. Kuznetsova M.V., Kuznetsova M.P., Afanasyevskaya E.V., Samartsev V.A. experimental grounds for using collagen-based anti-adhesion barrier coated with biocides for prevention of abdominal surgical infection. Sovremennye tehnologii v medicine 2018; 10(2): 66,
  133. Birindelli A., Sartelli M., Di Saverio S., Coccolini F., Ansaloni L., van Ramshorst G.H., Campanelli G., Khokha V., Moore E.E., Peitzman A., Velmahos G., Moore F.A., Leppaniemi A., Burlew C.C., Biffl W.L., Koike K., Kluger Y., Fraga G.P., Ordonez C.A., Novello M., Agresta F., Sakakushev B., Gerych I., Wani I., Kelly M.D., Gomes C.A., Faro M.P. Jr., Tarasconi A., Demetrashvili Z., Lee J.G., Vettoretto N., Guercioni G., Persiani R., Tranà C., Cui Y., Kok K.Y.Y., Ghnnam W.M., Abbas A.E., Sato N., Marwah S., Rangarajan M., Ben-Ishay O., Adesunkanmi A.R.K., Lohse H.A.S., Kenig J., Mandalà S., Coimbra R., Bhangu A., Suggett N., Biondi A., Portolani N., Baiocchi G., Kirkpatrick A.W., Scibé R., Sugrue M., Chiara O., Catena F. 2017 update of the 1 guidelines for emergency repair of complicated abdominal wall hernias. World J Emerg Surg 2017; 12: 37,
  134. Botezaty A.A., Railianu R.I., Marakutsa E.V., Monul S.G. Functionally reasonable methods of autoplasty in combination with the autodermoplasty in treatment of large and gigantic median hernia. Vestnik Pridnestrovskogo universiteta. Seriya: Mediko-biologicheskie i khimicheskie nauki 2017; 2(56): 12–18.
  135. Clay L., Stark B., Gunnarsson U., Strigård K. Full-thickness skin graft vs. synthetic mesh in the repair of giant incisional hernia: a randomized controlled multicenter study. Hernia 2018; 22(2): 325–332,
  136. López-Cano M., Quiles M.T., Pereira J.A., Armengol-Carrasco M., Arbós Vía M.A. Complex abdominal wall hernia repair in contaminated surgical fields: factors affecting the choice of prosthesis. Am Surg 2017; 83(6): 583–590.
  137. Atema J.J., Furnée E.J., Maeda Y., Warusavitarne J., Tanis P.J., Bemelman W.A., Vaizey C.J., Boermeester M.A. Major complex abdominal wall repair in contaminated fields with use of a non-cross-linked biologic mesh: a dual-institutional experience. World J Surg 2017; 41(8): 1993–1999,
  138. Montgomery A., Kallinowski F., Köckerling F. Evidence for replacement of an infected synthetic by a biological mesh in abdominal wall hernia repair. Front Surg 2015; 2: 67,
  139. Primus F.E., Harris H.W. A critical review of biologic mesh use in ventral hernia repairs under contaminated conditions. Hernia 2013; 17(1): 21–30,
  140. Ferzoco S.J. A systematic review of outcomes following repair of complex ventral incisional hernias with biologic mesh. Int Surg 2013; 98(4): 399–408,
  141. Atema J.J., de Vries F.E., Boermeester M.A. Systematic review and meta-analysis of the repair of potentially contaminated and contaminated abdominal wall defects. Am J Surg 2016; 212(5): 982–995,
  142. Köckerling F., Alam N.N., Antoniou S.A., Daniels I.R., Famiglietti F., Fortelny R.H., Heiss M.M., Kallinowski F., Kyle-Leinhase I., Mayer F., Miserez M., Montgomery A., Morales-Conde S., Muysoms F., Narang S.K., Petter-Puchner A., Reinpold W., Scheuerlein H., Smietanski M., Stechemesser B., Strey C., Woeste G., Smart N.J. What is the evidence for the use of biologic or biosynthetic meshes in abdominal wall reconstruction? Hernia 2018; 22(2): 249–269,
  143. Stoikes N.F.N., Scott J.R., Badhwar A., Deeken C.R., Voeller G.R. Characterization of host response, resorption, and strength properties, and performance in the presence of bacteria for fully absorbable biomaterials for soft tissue repair. Hernia 2017; 21(5): 771–782,
  144. Majumder A., Neupane R., Novitsky Y.W. Antibiotic coating of hernia meshes: the next step toward preventing mesh infection. Surg Technol Int 2015; 27: 147–153.
  145. Perez-Köhler B., Bayon Y., Bellón J.M. Mesh infection and hernia repair: a review. Surg Infect (Larchmt) 2016; 17(2): 124–137,
  146. Blatnik J.A., Thatiparti T.R., Krpata D.M., Zuckerman S.T., Rosen M.J., von Recum H.A. Infection prevention using affinity polymer-coated, synthetic meshes in a pig hernia model. J Surg Res 2017; 219: 5–10,
  147. Grafmiller K.T., Zuckerman S.T., Petro C., Liu L., von Recum H.A., Rosen M.J., Korley J.N. Antibiotic-releasing microspheres prevent mesh infection in vivo. J Surg Res 2016; 206(1): 41–47,
  148. Pérez-Köhler B., García-Moreno F., Brune T., Pascual G., Bellón J.M. Preclinical bioassay of a polypropylene mesh for hernia repair pretreated with antibacterial solutions of chlorhexidine and allicin: an in vivo study. PLoS One 2015; 10(11): e0142768,
  149. Ha A., Criman E.T., Kurata W.E., Matsumoto K.W., Pierce L.M. Evaluation of a novel hybrid viable bioprosthetic mesh in a model of mesh infection. Plast Reconstr Surg Glob Open 2017; 5(8): e1418,
  150. Mokhov E.M., Kadykov V.A., Sergeev A.N., Askerov E.M., Armasov A.R., Lyubskiy I.V., Serov E.V., Sakharov A.A., Sukhov A.D. Using of a new biologically active thread in a clinical practice. Sovremennye problemy nauki i obrazovaniya 2016; 5: 159. URL:
  151. Mokhov E.M., Sergeev A.N. Implantation antimicrobial prevention of infection in the surgery intervention area. Sibirskoe meditsinskoe obozrenie 2017; 3(105): 75–81.
  152. Kornilayev P.G., Plechev V.V. Implantation prevention of pyoinflammatory wound complications in abdominal surgery. Rossiyskiy elektronnyy nauchnyy zhurnal 2013; 1(1): 149–153.
  153. Plechev V.V., Kornilaev P.G., Feoktistov D.V., Shavaleev R.R., Khakamov T.Sh. Morphological assessment of the efficacy of preventive method for wound complications in implant hernioplasty. Meditsinskiy vestnik Bashkortostana 2014; 9(5): 41–44.
  154. Parshakov А.А., Gavrilov V.А., Samartsev V.А. Prevention of complications of incisional hernia repair: current problem state (review). Sovremennye tehnologii v medicine 2018; 10(2): 175,
  155. Sadava E.E., Krpata D.M., Gao Y., Novitsky Y.W., Rosen M.J. Does presoaking synthetic mesh in antibiotic solution reduce mesh infections? An experimental study. J Gastrointest Surg 2013; 17(3): 562–568,
  156. Samartsev V.A., Gavrilov V.A., Parshakov A.A., Kuznetsova M.V. Posterior separation hernioplasty TAR in treatment of postoperative ventral hernias W3. Permskiy meditsinskiy zhurnal 2017; 34(1): 35–42.
  157. Encheva Yu.A., Kuznetsova M.V., Rubtsova E.A., Afanasievskaya E.V., Samartsev V.A. Chlorhexidine and “Prontosan” effect on biofilm formed by Staphylococcus aureus (in vitro study). Permskiy meditsinskiy zhurnal 2015; 32(1): 84–91.
Parshikov V.V. Inflammatory Complications of the Abdominal Wall Prosthetic Repair: Diagnostics, Treatment, and Prevention (Review). Sovremennye tehnologii v medicine 2019; 11(3): 158,

Journal in Databases