Key words: edematoinfiltrative cancer of a mammary gland, nonadjuvant chemotherapy, objective response, medical pathomorphosis.
- Abstract
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The edematoinfiltrative cancer relates to a rare, but more aggressive variety of a mammary gland locally-spread cancer. Now a complex approach with a priority of chemotherapy is a standard in its treatment. Besides, the results are very unsatisfactory.
Aim of investigation is assessment of the nonadjuvant chemotherapy effectiveness in patients with a mammary gland edematoinfiltrative cancer.
Materials and Methods. An analysis of the direct and remote treatment results of 48 patients, treating according to the FAC scheme, is made. A comparison of the objective and pathomorphological response rate in the female-patients with the edematoinfiltrative cancer depending on a type of a nonadjuvant chemotherapy is made.
Results. An inclusion of taxans and herceptine into the inductive treatment schemes, as well as intensification of the chemotherapy modes, permit to achieve the better results compared to the standard anthracycline-containing scheme use.